Nickeleit V, Klimkait T, Binet IF, et al. Categories Z00-Z99 are provided for. Among 106 patients included in the study (mean follow up 4. BKV-mediated allograft dysfunction has been retrospectively identified in 1 to 5 percent of renal-transplant recipients, but the incidence of BKV nephropathy, risk factors for it, and appropriate. The overall incidence of pyelonephritis on biopsy was 3. Therefore, there is. This is the American ICD-10-CM version of T86. PREVALENCE AND TYPES OF DYSLIPIDEMIA. Code First. 19, p = 0. We report a case series of extrarenal pseudoaneurysm after kidney transplant with. FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. Glomerulonephritis is the primary cause of end-stage renal disease in up to 50 percent of those who go on to receive a renal transplant. This is the American ICD-10-CM version of Z94. However, vascular complications can impact renal allograft outcomes. The 2024 edition of ICD-10-CM N28. Sadegal et al. Z94. 0) Z94. ICD-10-CM Diagnosis Code Z94. Some kidneys do not regain function even with maximal antirejection therapy. 11 - kidney transplant rejection Epidemiology. 7 ± 13. Adenovirus was isolated from his urine. 1%, 92. Factors influencing health status and contact with health services. Z48. Delayed graft function (DGF) refers to the acute kidney injury that occurs in the first week of kidney transplantation that necessitates dialysis intervention. Medical. Kidney Transplantations From HBsAg-Positive Donors. Z94. These charges are not considered for the IPPS outlier calculation when a procedure code beginning with 556 is reported. The diagnosis of DGF is complicated by a. INTRODUCTION Graft Loss and Mortality. 5 [convert to ICD-9-CM] Skin transplant status. Despite increased rates of delayed graft function (DGF) after DCD kidney transplantation, first-time recipients of DCD kidneys (n = 739) or DBD kidneys (n = 6,759) showed no difference in 5-year graft survival (HR 1. Although kidney transplantation outcomes in the short term have shown significant gains over time, improvements in long-term outcomes have. T86. Biomarkers have emerged as valuable tools to. 19 became effective on. 6%), and death (2. By 10 years, after kidney transplant, up to 25% have developed de novo DSA (dnDSA). Purpose of Review This review provides a critical literature overview of the risks and benefits of transplantectomy in patients with a failed allograft. 4 Among the 458 patients studied, with 315 in the native kidney arm and 143 in the transplant kidney arm, the complication rate was 28. 50360 Renal allotransplantation, implantation of graft; without recipient nephrectomy 50365 Renal allotransplantation, implantation of graft; with recipient nephrectomy 50380 Renal autotransplantation, reimplantation of kidney 50547 Laparoscopy, surgical; donor nephrectomy (including cold preservation), from living donor ICD-9 Procedure: A single ICD-10 code for kidney transplant rejection (T86. ICD-10-CM Codes. 9 became effective on October 1, 2023. Acute kidney transplant rejection; Acute rejection of renal transplant; Chronic rejection. According to data from the OPTN, for individuals receiving primary kidney transplants between 2008 and 2015, the 1-, 3- and 5-year survival rates were 97. 101) performed poorly and. Indeed, AR itself has been repeatedly shown to be associated with. Graft survival of the transplanted kidney is documented in detail for the first years after transplantation in many publications. Donor-specific antibodies have become an established biomarker predicting antibody-mediated rejection. However, its impact on mortality and graft survival is still ambiguous. Kidney transplant failure. Showing 1-25: ICD-10-CM Diagnosis Code Z94. Therefore, the current study aimed to analyze if PTDM increases mortality and graft failure by pooling multivariable-adjusted data from individual studies. 18,19,23,28-29 Evidence continues to develop for other transplant. Chronic allograft nephropathy is the generic term to describe chronic interstitial fibrosis and tubular atrophy commonly seen in kidney transplants, which is responsible for most allograft losses, excluding recipient death. A kidney transplant is a surgery to place a healthy kidney from a living or deceased donor into a person whose kidneys no longer function properly. Introduction. Antibody mediated rejection has been reported to occur in about 5 - 10% of transplant patients (J Transplant 2012;2012:193724). Renal disease in the allograft recipient. The definitive diagnosis of PVAN requires an allograft biopsy, which shows intranuclear viral inclusions within tubular epithelial cells and positive immunohistochemical staining for viral antigens []. 13 [convert to ICD-9-CM] Kidney transplant infection. Therefore, there is a significant number of patients living with a functioning kidney allograft. The causes for graft loss are predominantly acute T cell-mediated rejection (TCMR), primary non-function in case of deceased donor donation, surgical complications, and increased risk of death because of cardiovascular events or infection. 19 is a billable diagnosis code used to specify a medical diagnosis of other complication of kidney transplant. 8 Other transplanted organ and tissue status. Hyperacute rejection is usually caused by specific antibodies against the graft and occurs within minutes or hours after grafting. 12 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Among kidney transplant recipients, BKPyV reactivation is common. According to data from the OPTN, for individuals receiving primary kidney transplants between 2008 and 2015, the 1-, 3- and 5-year survival rates were 97. It accounts for 1–5% cases of post-transplant hypertension . code to identify other transplant complications, such as:; graft-versus-host disease (D89. The 1-year and 3-year kidney graft survival rates for SPK DD were 92 % and 84 %, 94 % and 86 % for SPK DL, and 100 % and 89 % for SPK LL recipients, respectively (p ≥ 0. Subsequently, we studied 696 consecutive adult kidney allograft recipients that were grouped according to allograft type and histology at time-zero biopsy [DRTx/suboptimal histology (n = 194. Competing risk analysis could be useful to determine the impact of different events affecting graft survival, the occurrence of an outcome of interest can be precluded by another. 13. 9: Sepsis, unspecified organism: C24. Several risk factors to develop graft thrombosis depending on donors and recipients are well known. 50365. Several studies in kidney, liver, heart, and small bowel allograft recipients have demonstrated that low ATP levels (≤225 ng/mL) correlate with infection, while high levels (≥ 525 ng/mL) are associated with rejection. 1%, 92. In HSCT, the risk of disease is also higher both in seropositive recipients, regardless of the donor's serological status, and in the presence of graft-versus-host disease (GVHD) 12. 01, 95% CI 0. 1 The optimal treatment of AMR remains uncertain, in part caused by continuously evolving diagnostic. Radiologists play an integral role within the multidisci-plinary team in care of the transplant patient at every stage of the transplant process. 1) years. Although noninvasive imaging can detect an underlying stenosis, angiography with subsequent angioplasty or stenting, or both, provides definitive diagnosis. Antibody-mediated rejection is the leading cause of graft loss after kidney transplant. The incidence of CMV in the renal transplant population is estimated to be between 8 and 32 percent ( 2. Antibody-mediated rejection (ABMR) is the most common cause of immune-mediated allograft failure after kidney transplantation []. 61, I71. RCC post-RT can adversely affect. Renal impairment may occur before LT (functional or due to preexisting parenchymal kidney disease), in the peri-operative period or later after LT. 11 became effective on October 1, 2023. Loss of a renal allograft as a complication of biopsy is rare. The 2024 edition of ICD-10-CM T86. ICD-10 codes covered if selection criteria are met (not all-inclusive): I21. Posttransplantation diabetes mellitus (PTDM) is an important metabolic complication after KT that causes graft failure and cardiovascular complications in kidney transplantation (KT) recipients. Applicable To. 1993; 55: 752-756. Vella J. Transplantation physicians began to focus on late allograft changes, including chronic rejection, 17-19 which portends serious risks of allograft loss and death among recipients of kidney, heart. This is the American ICD-10-CM version of Z94. 83 Pancreas transplant status. This retrospective study on kidney transplantation was conducted from January 1, 2018, to December 31,. 7 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. This revision is retroactive effective for dates of service on or after 10/5/2021. 100) was present in 84% of true kidney transplant rejections and is an accurate way of identifying kidney. 12 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Objective To describe the long-term hemodialysis arteriovenous fistula (AVF) patency, incidence of AVF use, incidence and nature of AVF complications and surgery in patients after kidney transplantation. The investigators assessed the significance of immune cell function in 76 renal allograft recipients after anti-thymocyte globulin induction and initiation of maintenance immunosuppression. The causes of ESRD for renal transplantation were summarized in Table 1. Patients and methods We retrospectively analysed the AVF outcome and complications in all adult kidney allograft recipients transplanted. Under Article Text revised the title of the table to read, “Solid Organ Allograft Rejection Tests that meet coverage criteria of policy L38568” and revised the table to add the last row. Delayed graft function (DGF) refers to the acute kidney injury that occurs in the first week of kidney transplantation, which necessitates dialysis intervention. The total number of living kidney transplant recipients with a functioning graft is projected to surpass 250,000 in the next few years. 1%,. 7 - other international versions of ICD-10 Z94. Messenger RNA for FOXP3 in the urine of renal-allograft recipients. This is the American ICD-10-CM version of Z94. Current pillars of transplant monitoring are serum creatinine, proteinuria, and drug blood levels, which are considered as traditional markers, due to. Risk factors for chronic rejection in renal allograft recipients. The glomerular filtration rate (GFR) and levels of proteinuria are shown as measured after transplantation of the allograft in the first recipient, Patient 1 (beginning on day 0), and after. Allografts from 40 HCV Ab+/NAT- donors were transplanted to 52 HCV Ab- recipients between July 2016 and February 2018. A homozygous variant at the chromosome 2q12. 81 Bone marrow transplant status. 78 mins (range of 52 to 111) versus 222 mins (range of 74 to 326). 810 - T86. Epidemiologic studies have shown that up to 90% of some human populations become exposed to BK virus by adulthood. PTA is associated with increased graft loss and in most studies with increased mortality. 4 may differ. 6 Bone transplant status. Hospital admission following acute kidney injury in kidney transplant recipients is associated with a negative impact on graft function after 1-year. Effective and implementation dates 10/01/2000. 4 for Complications of liver transplant is a medical classification as listed by WHO under the range - Injury, poisoning and certain other consequences of external causes . Z94. Z94. showed that CMV infection causes a 1. 19 is a billable diagnosis code used to specify other complication of kidney transplant. Messenger RNA for FOXP3 in the urine of renal-allograft recipients. Abstract. 9 became effective on October 1, 2023. ICD-10 code T86. De novo HCV infection was detected at 3 months post-KT in one recipient (1. The actuarial kidney graft survival for patients with BKVN has improved in the past decade. Acute Kidney Injury in the Donor DGF and Risk of Graft Failure. The prevalence of PTxH among kidney recipients is between 55-90% [ 13 ], [ 14 ]. DSA are a result of B cell and plasma cell activation and bind to HLA and/or non-HLA molecules on the endothelium of the graft. There were 48 patients without DSAs; of those with DSAs, ABMR emerged in 20. 13 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. It has been estimated that 70% of kidney transplant recipients will experience an infection episode within the first 3 years after transplantation (Dharnidharka et al. After immunosuppression withdrawal, a diagnosis of graft intolerance syndrome was made based on clinical criteria and confirmed by the persistence of renal perfusion under imaging procedures. 81 - other international versions of ICD-10 Z94. 50365. Additionally, it offers a summary of related problems, primarily alloantibody sensitization in the event of nephrectomy and immunosuppression weaning. T86. 41: Liver transplant rejection: Z76. 9, and 47. 11 Read h/o: kidney dialysis. Renal transplantation (RT) is the preferred treatment for end-stage renal disease. However, urological complications are frequently observed, leading to both postoperative. The rate of primary non-function is 2–15%. Chronic renal failure after liver transplantation (LT) is significantly more frequent than after lung or heart transplantation and it results in an increased short and long-term mortality. This section shows you chapter-specific coding guidelines to increase your understanding and correct usage of the target ICD-10-CM Volume 1 code. The following ICD-10-CM codes have been revised: Group 1: I71. hemophagocytic syndrome has been reported as a rare complication of CMV infection in renal-transplant recipients. 1) years. Antiphospholipid syndrome (APS) is a devastating autoimmune disease and in renal transplant recipients may result in allograft thrombosis or in extra-renal manifestation, mostly venous thromboembolism. 29: Type 2 diabetes mellitus with other diabetic kidney complication; E10. Finally, brain death, in and of itself, induces an intense proinflammatory state, which may impact recipient immunity and graft function after kidney transplantation [ 1 ]. PloS One 10 , e0138944. Applicable To. The common causes of inguinal herniation of the transplant ureter are redundancy of transplant ureter [ 1] and anterior positioning of the ureter in relation to the spermatic cord. FSGS recurred in 57 patients (32%; 95% confidence interval [95% CI], 25% to 39%) and 39% of them lost their graft over a median of 5 (interquartile range, 3. 80 had higher mortality than those with a resistive index of less than 0. Includes: organ or tissue replaced by heterogenous or homogenous transplant. This is the American ICD-10-CM version of D47. tient concerns: A 76-year-old man, who was a renal transplant recipient, presented with bilateral pitting oedema, reduced urine output, and right inguinal hernia. Infections account for 16% of patient deaths and 7. In Brief. Encouraged by these results, two large phase III multi-centre trials enrolling nearly 1300 renal transplant recipients were performed in the US and Europe. 0 became effective on October 1, 2023. Abstract. 1964267. 9:. This is the American ICD-10-CM version of Z94. Physicians may document in the medical record that a kidney transplant recipient also has chronic kidney disease (CKD). ICD-10-CM Diagnosis Code T86. Failed renal transplant. 0. 81 and 584. 7 became effective on October 1, 2023. Background Page kidney (PK) is the occurrence of kidney hypoperfusion and ischemia due to pressure on the kidney by a subcapsular hematoma (SH), a mass, or fluid collection. In this study, ICD-8 (59010) and ICD-10 (DN109 and DN129) were used to identify hospitalisation of patients with pyelonephritis. Increasing donor or recipient age, repeat transplantation, and CIT >12 h were. Various factors influence the graft survival, infections being most common. The level of function of a transplanted kidney in the immediate postoperative period is correlated with long-term graft and patient survival [1–4]. Abstract. Renal allotransplantation; implementation of graft, excluding donor and recipient nephrectomy. The 2024 edition of ICD-10-CM Z94. The most affected kidney transplant group was the recipients (83%, 10/12). SH after renal transplantation may result in kidney ischemia and graft loss. Chronic allograft failure (CAF) is the leading cause of late graft loss in renal transplantation. 84 - other international versions of ICD-10 Z94. The mean age of renal transplant recipients (n = 152) was 38. 1-3 Effective immunosuppressive drugs, along with attention to cardiovascular disease 4 and prophylaxis against infection, 5 have significantly reduced rates of acute rejection (15. Donor derived cell free DNA (dd-cfDNA) is being employed as a biomarker that. 11 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Ureteral obstruction occurs in 2–10% of renal transplant patients post-operatively, usually presenting within the first few weeks, or the first year. Introduction. 0–8. Abstract. Transplant renal artery stenosis (TRAS) is the narrowing of the transplant renal artery, impeding blood flow to the allograft. 1 became effective on October 1, 2023. Summary Background Data. 10/01/2022 R8 Article revised and published on 10/20/2022 effective for dates of service on and after 10/01/2022 to reflect the Annual ICD-10-CM Code Updates. 3 Moreover, in a multicenter cohort study, antibody-mediated damage caused allograft. The following ICD-10-CM code has been added to the article: Group 2: I1A. ICD-10: T86: Reference: PMID:11544006 (TNF, IL10, TGFB, IFNG, HLA-DMA. Z94. The 1-, 3-, and 5-year survival rates for individuals receiving primary kidney transplants between 2008 and 2015 were 97. Among recipients of a kidney from a deceased donor, the incidence of delayed allograft function at 2 weeks (defined as persistent oliguria, a decrease in the serum creatinine level of less than 0. Z1) ICD-10-CM Diagnosis Code Z94. After the first. The targets of injury include the kidney tubular epithelium, the endothelium, and the glomerulus. Abstract. 1, 2 Prompt diagnosis and remedial treatment are vital to prevent graft loss. Z94. The overall incidence of pyelonephritis on biopsy was 3. 2, 98. Filiponi, T. Urinary CXCL-9 and CXCL-10 proteins as markers for kidney graft inflammation and alloimmune response. 19 contain annotation back-references that may be applicable to T86. Patients with primary renal graft thrombosis (arterial or venous) were excluded. In this article, we will present an overview of the common transplant-specific AKI etiologies that include increased susceptibility to hemodynamic-mediated AKI, acute. A total of 1947 kidney transplant recipients had kidney allograft biopsies due to an elevated serum creatinine (n = 773), aggravated proteinuria (n = 40), scheduled protocol (n = 1081), and other. • Preferentially used to higher-risk recipients (age above 60 y, dialysis access problems), and after informed consent. 2); post-transplant lymphoproliferative disorders (PTLD) (D47. Among 11,742 kidney transplant recipients screened for FSGS, 176 had a diagnosis of idiopathic FSGS and were included. RCC in donor. Allograft solid-organ transplantation has become a standard of care in patients with end-stage organ disease. Nevertheless, it should remain high on any differential diagnosis of unexplained graft dysfunction because of the potential negative effect on graft longevity. Z94. However, clinical challenges persist, i. BKV-mediated allograft dysfunction has been retrospectively identified in 1 to 5 percent of renal-transplant recipients, but the incidence of BKV nephropathy, risk factors for it, and appropriate. 7, 10, 19, 24, 26-28 Such an early diagnosis requires: (a) proper risk assessment of renal allograft recipients, and (b) optimal timing of a. Renal artery thrombosis is the leading cause of infarction. The 2024 edition of ICD-10-CM T86. However, viruria is typically asymptomatic or. This is the American ICD-10-CM version of T86. The incidence and pathological processes involved in chronic. CD8+ and CD4+ T cells of donor and recipient origin are present in the renal allograft. N Engl J Med 2005;353: 2342-2351. We then tested its ability to reclassify rejection diagnoses for adult and pediatric kidney transplant recipients in three international multicentric cohorts and two large prospective clinical. Figure 2 demonstrates the time course from 8 to 20 April 2020 over which the 54 SARS-CoV-2-positive cases occurred and the cumulative cases over time. ICD-10-CM Diagnosis Code T86. Chronic kidney disease (CKD) is increasing in most countries and kidney transplantation is the best option for those patients requiring renal replacement therapy. 1. Allogeneic stem cell transplantation (HSCT) is a procedure in which a portion of a healthy donor's stem cell or bone marrow is obtained and prepared for intravenous infusion. Since the hallmark kidney transplant in 1954, the standard. 7% of death censored graft failure in renal transplant patients. 4 - other international versions of ICD-10 Z52. Abstract. ICD-10-CM Codes. 0 - B99. The IFN pathway likely reflects activation mechanisms independent of the AHNAK program as there was not. This is the American ICD-10-CM version of Z52. For eligible patients with end-stage renal disease (ESRD), kidney transplantation is the preferred treatment option as it is associated with improved long-term survival, better quality of life, and lower health care costs compared with chronic dialysis. We aim at identifying factors associated with biopsy proven BKVN among KTR. Kidney allograft survival has increased substantially in the US over the past several decades, with USRDS reporting 93. Combined kidney-pancreas transplantation is the treatment of choice for patients who have type 1 diabetes and ESRD. This is primarily the consequence of the CNI adverse effects,. Injury, poisoning and certain other consequences of external causes. mismatched CPT-ICD-9 codes - with top Medicare carrier and private payer accepted diagnoses for the chosen CPT® code. Z94. 3%, respectively. The following code (s) above T86. Background Urinary tract infections (UTI) are the most common of infections after renal transplantation. T86. INTRODUCTION. History of kidney transplant; History of renal transplant. Delayed graft function (DGF), most commonly defined as the need for at least 1 dialysis treatment within the. 13 - other international versions of ICD-10 T86. 2 percent, respectively, for kidney allografts and. There are multiple causes, with iron deficiency being the major contributor. A and B, The use of aortic patches when the kidney is from a cadaveric donor is demon-strated. ). Z94. Polyomavirus nephropathy (PVN) is primarily caused by a productive intra-renal BK virus infection. 1% 1-year survival for patients transplanted with deceased donors and 96. Allograft dysfunction after a kidney transplant is often clinically asymptomatic and is usually detected as an increase in serum creatinine level with corresponding decrease in glomerular filtration rate. 2007). This is the American ICD-10-CM version of T86. Renal allotransplantation, implantation of graft; with recipient. T86. 9% and 86. Kidney transplantation represents the gold standard treatment option for patients with end-stage renal disease. DGF was associated with increased odds of graft failure, acute rejection, and mortality. Methods We conducted a retrospective case–control study. A few diseases are associated with a high risk of renal allograft loss, including focal segmental glomerulosclerosis, HUS oxalosis, and membranoproliferative glomerulonephritis. BK virus nephropathy (BKVN) is a serious opportunistic infection threatening renal function especially during the first year after transplantation. Thirty-three (82. A kidney transplant involves the surgical removal of a kidney from a deceased or living donor and implantation into a recipient. Ten kidney transplant recipients tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by polymerase chain reaction, and 9 were admitted. 1 The most common cause of. 04/2000 - Corrected ICD-9-CM code from 52. ICD-10: T86. Risk factors for chronic rejection in renal allograft recipients. • Donor kidney can be used for transplantation after excision of RCC if size <2–4 cm, nucleolar grade ≤II and clear surgical margins. Z52. . The influence of acute graft pyelonephritis (AGPN) on graft outcome in renal transplant recipients still remains controversial. In some patients, kidney transplantation alone is not optimal treatment. 84 Stem cells transplant status. Methods: In a cohort of 96 kidney transplant recipients, we performed 22-color spectral flow cytometry, RNA-seq and in vitro assays to profile circulating B cells, as well as multiplex immunofluorescence and RNA-seq to profile infiltrating B cells in allograft biopsies. " Long description: "Acute graft versus host disease due to kidney transplant; Acute on chronic graft versus. While several. 12 became effective on October 1, 2023. Its incidence has been reported as between 0. The salient features of active AMR include acute tissue injury, antibody interaction with vascular endothelium, and the presence of circulating donor-specific antibodies (DSA), with chronic active AMR diagnosed using. Case presentation We present a rare case of early spontaneous SH in an allograft kidney. To the Editor: Recurrent primary focal segmental glomerulosclerosis (FSGS) develops in over 40% of renal-transplant recipients and presents a major therapeutic challenge. Purpose of Review This review provides a critical literature overview of the risks and benefits of transplantectomy in patients with a failed allograft. 9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Improvements in surgical technique and pharmacologic treatment have continuously prolonged allograft survival in recent years. 3 BKV is a urotheliotropic. [ 2, 3] However, these conditions were not observed in our patient. Much of the focus of kidney transplantation is invested into guiding patients through listing, waitlist management, and transplant, with the goal of preserving allograft function for as long as possible (1,2). ICD-10-CM Diagnosis Code S35. 3%, respectively. In the discovery phase, 50 deletion-tagging SNPs were screened for association with biopsy-confirmed rejection in 705 kidney allograft recipients. Jun-Aug 2020;46-47:101690. New-onset diabetes mellitus after transplantation (NODAT) is a frequent complication in kidney allograft recipients. 0 [convert to ICD-9-CM] Kidney transplant status. Previously, we have shown that kidney transplant recipients with a failing graft had a higher hazard of death and a higher rate of all-cause hospitalization compared with matched, nontransplant controls. Risk factors for graft failure in kidney transplantation. The article is a comprehensive and updated resource for. Background: Antibody-mediated rejection (AMR) is one of the leading causes of graft loss in kidney transplant recipients but little is known about the associated cost and healthcare burden of AMR. What this adds. 4% (n = 101) as male and 33. This is the American ICD-10-CM version of T86. 1. 0 [convert to ICD-9-CM] Kidney transplant status. Complications of transplanted organs and tissue (T86) Kidney transplant rejection (T86. The 2024 edition of ICD-10-CM Z94. The present study was designed to study the role of the pro-phagocytic CRT and anti-phagocytic CD47 signals in patients with renal. BK is a circular, double-stranded DNA virus from the polyomavirus family. We aimed to identify the prevalence and. We retrospectively analysed all patients who received a kidney transplant and received follow up care in our centre between 2009–2019. Arteriovenous fistulas occur in up to 10%–16% of renal allograft biopsies (19, 20) and may only be detected with CCDS. 11) does not distinguish between T-cell mediated and antibody-mediated rejection, and this ICD-10 code was only added recently.